However, although there are many palliative therapies, such as transarterial chemoembolization (TACE), systemic chemotherapy, and radiation therapy, the prognosis of patients with advanced HCC or inoperability remains poor.Īmong the palliative therapeutic modalities, TACE is the current standard treatment for patients who are not candidates for curative therapies. 4 Prognosis of patients with early stage HCC or operability is relatively good due to availability of curative therapies such as surgical resection or liver transplantation, radiofrequency ablation (RFA), and percutaneous ethanol injection therapy (PEIT). A recent study reported that only 30% of patients with HCC are indicated to potentially curative treatments, even fewer in Asia. 2, 3 Thus, the number of cases of HCC with operability is very small. The reason may be associated with difficulty of detection of early HCC due to the rapidly-infiltrating growth pattern of HCC, simultaneous presence of multiple tumors, and ambiguity of HCC-related symptoms. 1 Despite the development of a number of modalities for treatment of HCC, the mortality associated with HCC is still high. doi: 10.12968/bjcn.2019.24.10.482.Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality together with lung and stomach cancers. (2019) Delivering chemotherapy at home: how much do we know? British Journal of Community Nursing. This disrupted the patients’ treatment schedule and, in some cases, resulted in sub-therapeutic dosing. Interestingly, a two-phase study that was carried out to observe and evaluate patients receiving ambulatory chemotherapy concluded that in 50% of the observed cases the infusion pump did not finish on time. Despite all the advantages, experiments carried out by the authors and others in the literature showed that the performance of these pumps varied depending on the temperature and/or viscosity of the diluent.
This minimises disruption to carers and families. Elastomeric pumps are preferred by the patients, as they get them connected at the hospital or cancer centres, then go back home where they can have visits from the district nursing team. Ambulatory devices such as elastomeric pumps can deliver prolonged infusions of a variety of chemotherapy agents.
Elastomeric pumps are preferred by the patients, as they get them connected at the hospital or cancer centres, then go back home where they can have visits from the district nursing team” Shereen and Salman (2019).Īmbulatory chemotherapy offers many advantages from supporting a closer to home treatment approach to lowering the cost of care.
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